验证数据展示
产品信息
17941-1-AP targets CLEC4C in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | CLEC4C fusion protein Ag12363 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | C-type lectin domain family 4, member C |
| 别名 | CLECSF7, CLECSF11, CD303, BDCA-2, BDCA2 |
| 计算分子量 | 213 aa, 25 kDa |
| GenBank蛋白编号 | BC074968 |
| 基因名称 | CLEC4C |
| Gene ID (NCBI) | 170482 |
| RRID | AB_2878469 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8WTT0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CLEC4C (C-type lectin domain family 4 member C), also known as DLEC, BDCA-2, CD303, and HECL, is a type II membrane protein that contains one C-type lectin domain. The C-type lectin domain family members share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC4C is a specific surface marker of human plasmacytoid dendritic cells, centrally involved in antigen presentation and immune tolerance. (PMID: 15481152; PMID: 15476922; PMID: 34486917; PMID: 23847189)