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CLSTN3 Monoclonal antibody, PBS Only (Capture)

CLSTN3 Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3D4F8

Cat no : 68855-3-PBS

Print datasheet

Synonyms

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta

验证数据展示

  • Cytometric bead array standard curve of MP50250-2

    Cytometric bead array standard curve of MP50250-2

    Cytometric bead array standard curve of MP50250-2, CLSTN3 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68855-3-PBS. Detection antibody: 68855-2-PBS. Standard:Ag14897. Range: 3.125-50 ng/mL.

产品信息

68855-3-PBS targets CLSTN3 as part of a matched antibody pair:

MP50250-2: 68855-3-PBS capture and 68855-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CLSTN3 fusion protein Ag14897 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name calsyntenin 3
Synonyms Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta
Calculated Molecular Weight 968 aa, 107 kDa
GenBank Accession NumberBC039075
Gene Symbol CLSTN3
Gene ID (NCBI) 9746
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G Magarose purification
UNIPROT IDQ9BQT9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).