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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84924-7-RR (same clone as 84924-7-PBS)

    WB analysis using 84924-7-RR (same clone as 84924-7-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84924-7-RR (CNDP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

  • IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    Immunohistochemical analysis of paraffin-embedded rat stomach tissue slide using 84924-7-RR (CNDP2 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

  • IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    IHC staining of rat stomach using 84924-7-RR (same clone as 84924-7-PBS)

    Immunohistochemical analysis of paraffin-embedded rat stomach tissue slide using 84924-7-RR (CNDP2 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84924-7-PBS in a different storage buffer formulation.

CNDP2 Recombinant antibody, PBS Only

CNDP2 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84924-7-PBS

产品说明书

CloneNo. 242373E4

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

242373E4, CNDP dipeptidase 2, CPGL, Cytosolic non-specific dipeptidase, EC:3.4.13.18

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84924-7-PBS targets CNDP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CNDP2 fusion protein Ag6684 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CNDP dipeptidase 2 (metallopeptidase M20 family)
别名 242373E4, CNDP dipeptidase 2, CPGL, Cytosolic non-specific dipeptidase, EC:3.4.13.18
计算分子量 53 kDa
观测分子量 44-53 kDa
GenBank蛋白编号BC001375
基因名称 CNDP2
Gene ID (NCBI) 55748
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ96KP4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Carnosine dipeptidase II (CNDP2) catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. It has high dipeptidase activity toward cysteinyl glycine, an intermediate metabolite in glutathione metabolism (PubMed:19346245, PubMed:12473676). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). CNDP2 has 2 isoforms with a molecular weight of 53 and 44 kDa.
The isoform 1 is ubiquitously expressed with higher levels in the kidney and liver (at protein level) and expressed in peripheral blood leukocytes (PubMed:12473676). It is also expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at the protein level) (PubMed:24395568). Isoform 2 is broadly expressed in fetal tissues and expressed in the adult liver and placenta. (PMID: 17121880).