验证数据展示
产品信息
83615-4-PBS targets CNOT4 as part of a matched antibody pair:
MP00593-1: 83615-4-PBS capture and 83615-3-PBS detection (validated in Cytometric bead array)
MP00593-2: 83615-4-PBS capture and 83615-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, IHC, IF/ICC, FC (Intra), Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | CNOT4 fusion protein Ag3163 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | CCR4-NOT transcription complex, subunit 4 |
别名 | E3 ubiquitin-protein ligase CNOT4, CLONE243, CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, CCR4 associated factor 4 |
计算分子量 | 575 aa, 64 kDa |
观测分子量 | 64-85 kDa |
GenBank蛋白编号 | BC035590 |
基因名称 | CNOT4 |
Gene ID (NCBI) | 4850 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O95628 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CNOT4, also known as CCR4-NOT transcription complex subunit 4 , has E3 ubiquitin ligase activity, and promotes ubiquitination and degradation of target proteins. CNOT4 is involved in activation of the JAK/STAT pathway. CNOT4 exist many isoforms and the range of its molecular weight from 48 to 84 kDa.