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- KD/KO Validated
COMP Polyclonal antibody
COMP Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
ELISA and More (3)
Conjugate
Unconjugated
验证数据展示
产品信息
13641-1-AP targets COMP in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IF, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse, rat |
| Immunogen | COMP fusion protein Ag4575 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | cartilage oligomeric matrix protein |
| Synonyms | COMP, EDM1, EPD1, MED, PSACH, THBS5, Thrombospondin 5, TSP5 |
| Calculated Molecular Weight | 757 aa, 83 kDa |
| GenBank Accession Number | BC033676 |
| Gene Symbol | COMP |
| Gene ID (NCBI) | 1311 |
| RRID | AB_2877963 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P49747 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
COMP is a secreted pentameric glycoprotein built from modular units and belongs to the thrombospondin protein family. COMP is expressed by hypertrophic chondrocytes and osteoblasts during endochondral ossification, and its expression is increased during fracture healing. COMP is involved in the assembly of collagen fibrils and other structural matrix components. COMP interacts with a number of cartilage ECM proteins, including fibronectin, collagen I, II IX, XII, and XIV, matrilins, as well as proteoglycans such as aggrecan and others.
发表文章
| Species | Application | Title |
|---|---|---|
J Clin Invest Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. | ||
Cell Prolif Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway. | ||
Nat Commun Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.
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