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CORO1C Monoclonal antibody

CORO1C Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1B10G4

Cat no : 68846-1-Ig

Print datasheet

Synonyms

CRN2, Coronin-3, Coronin-1C, Coronin 3, Coronin 1C

验证数据展示

  • WB analysis using 68846-1-Ig

    WB analysis using 68846-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 68846-1-Ig (CORO1C antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

  • WB analysis using 68846-1-Ig

    WB analysis using 68846-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 68846-1-Ig (CORO1C antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inhTERT-RPE1 cells, HSC-T6 cells, NIH/3T3 cells, 4T1 cells, MDA-MB-231 cells, A549 cells, A431 cells, HepG2 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

68846-1-Ig targets CORO1C in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen CORO1C fusion protein Ag6546 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name coronin, actin binding protein, 1C
Synonyms CRN2, Coronin-3, Coronin-1C, Coronin 3, Coronin 1C
Calculated Molecular Weight 53 kDa
Observed Molecular Weight 57 kDa
GenBank Accession NumberBC002342
Gene Symbol CORO1C
Gene ID (NCBI) 23603
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9ULV4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CORO1C also known as HCRNN4, belongs to the WD repeat coronin family. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. It was reported to regulate actin‐dependent processes by assembling F-actin. CORO1C promoted the invasion of breast cancer and glioma cells by specifically promoting the formation of invadopodia(PMID: 30974047).

实验方案

Product Specific Protocols
WB protocol for CORO1C antibody 68846-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols