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  • KD/KO Validated

COX16 Polyclonal antibody

COX16 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 19425-1-AP

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Synonyms

PTD019, MC4DN22, HSPC203, hCOX16, COX 16



经过测试的应用

Positive WB detected inA549 cells, HeLa cells, SH-SY5Y cells
Positive IHC detected inhuman stomach tissue, human ovary cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

19425-1-AP targets COX16 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Immunogen COX16 fusion protein Ag13756 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
Synonyms PTD019, MC4DN22, HSPC203, hCOX16, COX 16
Calculated Molecular Weight 106 aa, 12 kDa
Observed Molecular Weight 12 kDa
GenBank Accession NumberBC001702
Gene Symbol COX16
Gene ID (NCBI) 51241
RRIDAB_10666854
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9P0S2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

实验方案

Product Specific Protocols
WB protocol for COX16 antibody 19425-1-APDownload protocol
IHC protocol for COX16 antibody 19425-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Mol Cell

Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery

Authors - Jasmin Adriana Schafer
humanWB

Nat Commun

Coordination of metal center biogenesis in human cytochrome c oxidase.

Authors - Eva Nývltová
humanWB

Elife

COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.

Authors - Abhishek Aich
  • KO Validated
humanWB

J Biol Chem

An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.

Authors - Xiaofen Jin
mouseWB

Redox Biol

Lead aggravates Alzheimer's disease pathology via mitochondrial copper accumulation regulated by COX17

Authors - Dingbang Huang
humanWB

iScience

Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis

Authors - Yunfan He