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CP21R7

CP21R7 (CP21) 是一种 GSK-3β抑制剂，其 IC50=1.8 nM。它也是一种 PKCα抑制剂，其 IC50=1900 nM。

CAS号

125314-13-8

分子式

C19H15N3O2

主要靶点

PKC|GSK-3

仅限科研使用

Cat No : CM04329

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Synonyms

CP21

验证数据展示

  • CAS No.: 125314-13-8

    CP21R7
    CAS#: 125314-13-8

产品信息

CP21R7 is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.

CAS号 125314-13-8
分子式 C19H15N3O2
主要靶点 PKC|GSK-3
主要通路 PI3K/Akt/mTOR信号通路|表观遗传|干细胞|细胞骨架
分子量 317.3
纯度 98.21%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 CP21

靶点活性

GSK-3β:1.8 nM|PKCα:1900 nM.

溶解度

Ethanol:1 mg/mL (3.15 mM),DMSO:59 mg/mL (185.9 mM),H2O:<1 mg/mL

参考文献

1.Gong L, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1693-6. 2.Sahara M, et al. Cell Res. 2015 Jan;25(1):148. 3.Patsch C, et al. Nat Cell Biol. 2015 Aug;17(8):1994-12003. 4.Sahara M, et al. Cell Res. 2014 Jul;24(7):820-41.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2