CPNE6 Polyclonal antibody

CPNE6 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA and More (3)

Conjugate

Unconjugated

Cat no : 13782-1-AP

Print datasheet

Synonyms

Copine 6, Copine VI, copine VI (neuronal), CPNE6, N COPINE, Neuronal copine



经过测试的应用

Positive WB detected inmouse brain tissue, rat brain tissue
Positive IHC detected inrat dorsal root ganglion tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:12000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13782-1-AP targets CPNE6 in WB, IP, IF, IHC, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB, IP, IF, CoIP
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen CPNE6 fusion protein Ag4789 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name copine VI (neuronal)
Synonyms Copine 6, Copine VI, copine VI (neuronal), CPNE6, N COPINE, Neuronal copine
Calculated Molecular Weight 557 aa, 62 kDa
Observed Molecular Weight 65 kDa
GenBank Accession NumberBC018046
Gene Symbol CPNE6
Gene ID (NCBI) 9362
RRIDAB_2292172
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO95741
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Copines are a family of evolutionarily conserved calcium-dependent phospholipid-binding proteins (PMID: 9430674). They contain two Ca(2+)- and phospholipid-binding domains known as C2 domains. Copines are potentially involved in regulating membrane trafficking and in protein-protein interactions.

实验方案

Product Specific Protocols
WB protocol for CPNE6 antibody 13782-1-APDownload protocol
IHC protocol for CPNE6 antibody 13782-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Front Mol Neurosci

Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice

Authors - Xiaoxia Li
human, ratWB,IF

J Neurol Sci

Increased expression of copine VI in patients with refractory epilepsy and a rat model.

Authors - Binglin Zhu
human,ratIP,WB,CoIP

Cell Rep

Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis

Authors - Jing Zhi Anson Tan