验证数据展示
产品信息
66072-1-PBS targets CPT1C in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, pig |
免疫原 | CPT1C fusion protein Ag17963 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | carnitine palmitoyltransferase 1C |
别名 | CATL1, CPT IC, CPT1 B, CPT1C, CPT1P, CPTI B, CPTIC |
计算分子量 | 792 aa, 90 kDa |
观测分子量 | 82 kDa |
GenBank蛋白编号 | BC029104 |
基因名称 | CPT1C |
Gene ID (NCBI) | 126129 |
RRID | AB_11042325 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q8TCG5 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CPT1C, also named as CATL1, CPTI-B and B-CPTI, belongs to the carnitine/choline acetyltransferase family. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1C is an active forms of related brain-type carnitine palmitoyltransferase I. CPT1C may be a regulated target of malonyl-CoA that relays the "malonyl-CoA signal" in hypothalamic neurons that express the orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. (PMID: 17018521 ) This antibody can bind the close sequences genes.