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CRLF3 Polyclonal antibody

CRLF3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11567-1-AP

Print datasheet

Synonyms

CREME 9, CREME9, CRLF3, CYTOR4, FRWS, P48

验证数据展示

  • WB analysis using 11567-1-AP

    WB analysis using 11567-1-AP

    U-251 cells were subjected to SDS PAGE followed by western blot with 11567-1-AP (CRLF3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inU-251 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11567-1-AP targets CRLF3 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen CRLF3 fusion protein Ag2144 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name cytokine receptor-like factor 3
Synonyms CREME 9, CREME9, CRLF3, CYTOR4, FRWS, P48
Calculated Molecular Weight 442 aa, 50 kDa
Observed Molecular Weight51 kDa
GenBank Accession NumberBC023567
Gene Symbol CRLF3
Gene ID (NCBI) 51379
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8IUI8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Cytokine receptor-like factor 3 (CRLF3), a member of the group 1 in the prototypic class I cytokine receptors, contains the conserved cytokine receptor motif WSXWS, a single transmembrane segment and an intracellular Janus kinase (JAK) docking site (PMID: 31680856). CRLF3 is expressed in most normal human tissues and many tumor cell lines and has been reported to negatively regulate cell cycle progression (PMID: 19427400). CRLF3 has been identified as a human neuroprotective EV-3 (Epo) receptor (PMID: 37168680). It is involved neurogenesis, neuron survival, and dendritic development (PMID: 34233200).

实验方案

Product Specific Protocols
WB protocol for CRLF3 antibody 11567-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols