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CTDSP1 Polyclonal antibody

CTDSP1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 10952-1-AP

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Synonyms

NLIIF, NLI IF, NIF3, EC:3.1.3.16, CTDSP 1



经过测试的应用

Positive WB detected inHepG2 cells, mouse kidney tissue, mouse liver tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10952-1-AP targets CTDSP1 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Immunogen CTDSP1 fusion protein Ag1410 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Synonyms NLIIF, NLI IF, NIF3, EC:3.1.3.16, CTDSP 1
Calculated Molecular Weight 29 kDa
Observed Molecular Weight 29-33 kDa
GenBank Accession NumberBC012977
Gene Symbol CTDSP1
Gene ID (NCBI) 58190
RRIDAB_2087073
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9GZU7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CTDSP1 also named as NIF3, NLIIF, or SCP1, is a 261 amino acid protein, which contains one FCP1 homology domain. CTDSP1 localizes in the nucleus and colocalizes with RNA polymerase II. CTDSP1 is expressed in non-neuronal tissues. It is highly expressed in skeletal muscle, spleen, lung and placenta. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2.

实验方案

Product Specific Protocols
WB protocol for CTDSP1 antibody 10952-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

J Biol Chem

Phosphatase activity of Small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).

Authors - Nathaniel Tate Burkholder
  • KD Validated
humanWB

Cell Death Dis

MicroRNA-26a/b have protective roles in oral lichen planus.

Authors - Jie Du
humanWB

Iran J Basic Med Sci

MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma

Authors - Chunming Zhao
mouseWB

Cell Mol Neurobiol

Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway

Authors - Kang-Long Zhang