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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    WB analysis of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    A375 cells were subjected to SDS PAGE followed by western blot with 83629-1-RR (CTHRC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83629-1-PBS in a different storage buffer formulation.

  • FC experiment of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    FC experiment of A375 using 83629-1-RR (same clone as 83629-1-PBS)

    1x10^6 A375 cells were intracellularly stained with 0.25 ug CTHRC1 Recombinant antibody (83629-1-RR, Clone:240442E1) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011). This data was developed using the same antibody clone with 83629-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83629-1-RR

    Affinity and Kinetic Characterization of 83629-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83629-1-RR against Human CTHRC1 were performed. The affinity constant is 72.9 pM.

CTHRC1 Recombinant antibody, PBS Only

CTHRC1 Uni-rAbTM Recombinant Antibody for WB, FC (Intra), ELISA
Cat No. 83629-1-PBS

产品说明书

CloneNo. 240442E1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC (Intra), ELISA

别名

UNQ762/PRO1550, Protein NMTC1, Collagen triple helix repeat-containing protein 1, collagen triple helix repeat containing 1, 240442E1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83629-1-PBS targets CTHRC1 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC (Intra), ELISA Application Description
经测试反应性 human
免疫原 CTHRC1 fusion protein Ag9812 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 collagen triple helix repeat containing 1
别名 UNQ762/PRO1550, Protein NMTC1, Collagen triple helix repeat-containing protein 1, collagen triple helix repeat containing 1, 240442E1
计算分子量 243 aa, 26 kDa
观测分子量 25 kDa
GenBank蛋白编号BC014245
基因名称 CTHRC1
Gene ID (NCBI) 115908
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ96CG8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Collagen triple helix repeat-containing protein 1 (CTHRC1), also known as protein NMTC1, is a glycosylated secreted protein. CTHRC1 was identified as a novel molecular in injured and diseased arteries where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration (PMID: 15618538). It has been reported that CTHRC1 is a positive regulator of osteoblastic bone formation (PMID: 18779865). Besides, studies reveal that CTHRC1 expression is implicated in various malignancies, including hepatocellular carcinoma, gastric carcinoma, colon cancer, and lung cancer (PMID: 23922981; 24504172; 24746208; 25139095).