• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CX3CL1 Polyclonal antibody, PBS Only

CX3CL1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10108-2-PBS

Print datasheet

Synonyms

C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, C3Xkine, C X3 C motif chemokine 1, ABCD 3

验证数据展示

  • WB analysis of PC-3 using 10108-2-AP (same clone as 10108-2-PBS)

    WB analysis of PC-3 using 10108-2-AP (same clone as 10108-2-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 10108-2-AP (CX3CL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 10108-2-AP (CX3CL1 antibody) at dilution of 1:400 (under 10x lens).. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CX3CL1 antibody included
  • IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 10108-2-AP (CX3CL1 antibody) at dilution of 1:400 (under 40x lens).. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CX3CL1 antibody included
Planning an IHC experiment? We recommend our IHCeasy CX3CL1 Ready-To-Use IHC Kit. CX3CL1 primary antibody included.

产品信息

10108-2-PBS targets CX3CL1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CX3CL1 fusion protein Ag0161 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chemokine (C-X3-C motif) ligand 1
Synonyms C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, C3Xkine, C X3 C motif chemokine 1, ABCD 3
Calculated Molecular Weight 42 kDa
Observed Molecular Weight 90-100 kDa
GenBank Accession NumberBC001163
Gene Symbol CX3CL1
Gene ID (NCBI) 6376
RRIDAB_2087154
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP78423
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. The human CX3C chemokine carries the chemokine domain on top of an extended mucin-like stalk. CX3CL1 is synthesized as a 50-75 kDa precursor and undergoes glycosylation to yield two mature forms: a 100 kDa cell membrane bound form and an 85 kDa soluble form which is released from the cell surface. The soluble CX3C chemokine has potent chemoattractant activity for T cells and monocytes, and the cell-surface-bound protein, which is induced by primary proinflammatory signals in activated primary endothelial cells, promotes strong adhesion of those leukocytes.