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验证数据展示

  • WB analysis of PC-3 using 10108-2-AP (same clone as 10108-2-PBS)

    WB analysis of PC-3 using 10108-2-AP (same clone as 10108-2-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 10108-2-AP (CX3CL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 10108-2-AP (CX3CL1 antibody) at dilution of 1:400 (under 10x lens).. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CX3CL1 antibody included
  • IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    IHC staining of human small intestine using 10108-2-AP (same clone as 10108-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 10108-2-AP (CX3CL1 antibody) at dilution of 1:400 (under 40x lens).. This data was developed using the same antibody clone with 10108-2-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CX3CL1 antibody included

CX3CL1 Polyclonal antibody, PBS Only

CX3CL1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 10108-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, C3Xkine, C X3 C motif chemokine 1, ABCD 3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CX3CL1 Ready-To-Use IHC Kit. CX3CL1 primary antibody included.

产品信息

10108-2-PBS targets CX3CL1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CX3CL1 fusion protein Ag0161 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chemokine (C-X3-C motif) ligand 1
别名 C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, C3Xkine, C X3 C motif chemokine 1, ABCD 3
计算分子量 42 kDa
观测分子量 90-100 kDa
GenBank蛋白编号BC001163
基因名称 CX3CL1
Gene ID (NCBI) 6376
RRIDAB_2087154
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP78423
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. The human CX3C chemokine carries the chemokine domain on top of an extended mucin-like stalk. CX3CL1 is synthesized as a 50-75 kDa precursor and undergoes glycosylation to yield two mature forms: a 100 kDa cell membrane bound form and an 85 kDa soluble form which is released from the cell surface. The soluble CX3C chemokine has potent chemoattractant activity for T cells and monocytes, and the cell-surface-bound protein, which is induced by primary proinflammatory signals in activated primary endothelial cells, promotes strong adhesion of those leukocytes.