Anti-Human CXCL10/IP-10 Rabbit Recombinant Antibody

CXCL10/IP-10 Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98265-1-RR

产品说明书

CloneNo. 242013E12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

CXCL10, CXCL10/IP10, IP10, CXCL 10, C-X-C motif chemokine 10

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive FC (Intra) detected inIFN gamma and brefeldin A treated human PBMCs
Planning an IHC experiment? We recommend our IHCeasy CXCL10/IP10 Ready-To-Use IHC Kit. CXCL10/IP10 primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98265-1-RR targets CXCL10/IP-10 in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-X-C motif) ligand 10
别名 CXCL10, CXCL10/IP10, IP10, CXCL 10, C-X-C motif chemokine 10
计算分子量 11 kDa
GenBank蛋白编号BC010954
基因名称 CXCL10
Gene ID (NCBI) 3627
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP02778
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

CXCL10 (also known as IP-10) is a member of the CXC chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 is a 12-kDa protein and constitutes two internal disulfide cross bridges. The predicted signal peptidase cleavage generates a 10-kDa secreted polypeptide with four conserved cysteine residues in the N-terminal. The CXCL10 gene localizes on chromosome 4 at band q21, a locus associated with an acute monocytic/B-lymphocyte lineage leukemia exhibiting translocation of t (4; 11) (q21; q23). CXCL10 mediates leukocyte trafficking, adaptive immunity, inflammation, haematopoiesis and angiogenesis. Under proinflammatory conditions CXCL10 is secreted from a variety of cells, such as leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, stromal cells (fibroblasts) and keratinocytes in response to IFN-γ.

实验方案

Product Specific Protocols
FC protocol for CXCL10/IP-10 antibody 98265-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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