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CXCR6 Recombinant antibody, PBS Only

CXCR6 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241662E5

Cat no : 84591-1-PBS

Print datasheet

Synonyms

CXCR 6, CXC R6, CDw186, CD186, BONZO

验证数据展示

  • WB analysis using 84591-1-RR (same clone as 84591-1-PBS)

    WB analysis using 84591-1-RR (same clone as 84591-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84591-1-RR (CXCR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84591-1-RR (same clone as 84591-1-PBS)

    IHC staining of mouse brain using 84591-1-RR (same clone as 84591-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84591-1-RR (CXCR6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84591-1-PBS in a different storage buffer formulation.

产品信息

84591-1-PBS targets CXCR6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name chemokine (C-X-C motif) receptor 6
Synonyms CXCR 6, CXC R6, CDw186, CD186, BONZO
Calculated Molecular Weight 39 kDa
Observed Molecular Weight45 kDa
GenBank Accession NumberBC033584
Gene Symbol CXCR6
Gene ID (NCBI) 10663
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO00574
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCR6, or C-X-C chemokine receptor 6, is a G protein-coupled receptor with seven transmembrane domains that belong to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. CXCR6 is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signaling pathway that regulates T lymphocyte migration to various peripheral tissues such as the liver, spleen red pulp, intestine, lungs, and skin. CXCR6 plays a crucial role in immunosurveillance through its interaction with epithelial cells and certain subpopulations of intratumor dendritic cells (DC), particularly DC3, which express CXCL16 at the membrane.