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  • Featured Product
  • KD/KO Validated

CXCR7 Polyclonal antibody, PBS Only

CXCR7 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 20423-1-PBS

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Synonyms

验证数据展示

  • WB analysis of Raji using 20423-1-AP (same clone as 20423-1-PBS)

    WB analysis of Raji using 20423-1-AP (same clone as 20423-1-PBS)

    Raji cells were subjected to SDS PAGE followed by western blot with 20423-1-AP (CXCR7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

  • IP experiment of HUVEC using 20423-1-AP (same clone as 20423-1-PBS)

    IP experiment of HUVEC using 20423-1-AP (same clone as 20423-1-PBS)

    IP result of anti-CXCR7 (IP:20423-1-AP, 3ug; Detection:20423-1-AP 1:500) with HUVEC cells lysate 1400ug. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

    IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20423-1-AP (CXCR7 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

    IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20423-1-AP (CXCR7 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

产品信息

20423-1-PBS targets CXCR7 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen CXCR7 fusion protein Ag14247 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chemokine (C-X-C motif) receptor 7
Synonyms
Calculated Molecular Weight 362 aa, 41 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC036661
Gene Symbol CXCR7
Gene ID (NCBI) 57007
RRIDAB_10693619
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP25106
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).