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CXXC5 Recombinant antibody, PBS Only

CXXC5 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241034A6

Cat no : 83940-7-PBS

Print datasheet

Synonyms

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

验证数据展示

  • WB analysis using 83940-7-RR (same clone as 83940-7-PBS)

    WB analysis using 83940-7-RR (same clone as 83940-7-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83940-7-RR (CXXC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83940-7-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83940-7-RR

    Affinity and Kinetic Characterization of 83940-7-RR

    Biolayer interferometry (BLl) kinetic assays of 83940-7-RR against Human CXXC5 were performed. The affinity constant is 5.73 nM.

Planning an IHC experiment? We recommend our IHCeasy CXXC5 Ready-To-Use IHC Kit. CXXC5 primary antibody included.

产品信息

83940-7-PBS targets CXXC5 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CXXC5 fusion protein Ag9733 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CXXC finger 5
Synonyms Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5
Calculated Molecular Weight322aa,33 kDa; 227aa,24 kDa
Observed Molecular Weight 33-40 kDa
GenBank Accession NumberBC017439
Gene Symbol CXXC5
Gene ID (NCBI) 51523
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ7LFL8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812).