验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CYBB/NOX2 Ready-To-Use IHC Kit. CYBB/NOX2 primary antibody included.
发表文章中的应用
| WB | See 1 publications below |
产品信息
13525-1-AP targets NOX2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, rat |
| 免疫原 | NOX2 fusion protein Ag4402 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | cytochrome b-245, beta polypeptide |
| 别名 | |
| 计算分子量 | 577 aa, 65 kDa |
| GenBank蛋白编号 | BC032720 |
| 基因名称 | NOX2 |
| Gene ID (NCBI) | 1536 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P04839 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
NOX2, also named as CYBB, CGD, 91-phox, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, cytochrome b-245 and beta polypeptide, is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. CYBB participates in the regulation of cellular pH and is blocked by zinc.