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CYP24A1 Recombinant antibody, PBS Only

CYP24A1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242142F2

Cat no : 84821-3-PBS

Print datasheet

Synonyms

CYP24, CP24, 24-OHase, 242142F2, 24 OHase

验证数据展示

  • WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

    WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84821-3-RR (CYP24A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84821-3-PBS in a different storage buffer formulation.

产品信息

84821-3-PBS targets CYP24A1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen CYP24A1 fusion protein Ag17089 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name cytochrome P450, family 24, subfamily A, polypeptide 1
Synonyms CYP24, CP24, 24-OHase, 242142F2, 24 OHase
Calculated Molecular Weight 514 aa, 59 kDa
Observed Molecular Weight51 kDa
GenBank Accession NumberBC109083
Gene Symbol CYP24A1
Gene ID (NCBI) 1591
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ07973
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP24A1(1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and 1-alpha,25-dihydroxyvitamin D3. Cholecalciferol is metabolized by the 25-hydroxylases (CYP2R1 and CYP27A1) in the liver before 25-hydroxycholecalciferol (25(OH)D3) relocates to the circulation (PMID:20362668). The gene CYP24A1 has three isoforms, for the transit peptide "mitochondrial domain" removed, the MW of CYP24A1 will be 55-59 kDa, 47-51 kDa, and 43 kDa. This antibody is specific to CYP24A1.