验证数据展示
产品信息
67419-1-PBS targets CYP2W1 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, IF/ICC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | CYP2W1 fusion protein Ag29982 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
别名 | EC:1.14.14.-, Cytochrome P450 2W1, CYPIIW1, 2B10H2 |
计算分子量 | 54 kDa |
观测分子量 | 45-54 kDa |
GenBank蛋白编号 | BC025761 |
基因名称 | CYP2W1 |
Gene ID (NCBI) | 54905 |
RRID | AB_2882659 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q8TAV3 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cytochrome P450s have been proposed to be of importance both in carcinogenesis, by activating precarcinogens, and as determinants of cancer chemotherapy, where they participate in activation or inactivation of anti-cancer drugs. CYP2W1 is exclusively expressed in transformed tissue in the adult human, mainly in colon tumors. It is a potential drug target in cancer therapy. CYP2W1 has a molecular weight of 52-54 kDa, and 30/45 kDa of potential isoforms.