Carbenoxolone disodium

Carbenoxolone disodium (Duogastrone) 是甘草酸的活性代谢物和人11β-HSD 和细菌3α, 20β-HSD 的抑制剂。它是一种缝隙连接的解耦剂,可抑制牛痘病毒生长,用于消化性、食道和口腔溃疡和炎症的相关研究。

CAS号

7421-40-1

分子式

C34H48Na2O7

主要靶点

Gap Junction Protein

仅限科研使用

Cat No : CM15799

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Synonyms

甘珀酸钠|Duogastrone|Bioral|Biogastrone



产品信息

Carbenoxolone disodium salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.

CAS号 7421-40-1
分子式 C34H48Na2O7
主要靶点 Gap Junction Protein
主要通路 细胞骨架
分子量 614.72
纯度 98.01%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 甘珀酸钠|Duogastrone|Bioral|Biogastrone

溶解度

H2O:162.7 mM,DMSO:37.4 mM

参考文献

1.Hausmann W, Tárnoky AL. Br J Pharmacol ChemOthers. 1966 Feb;26(2):412-20.
2.Zhang H, Wei Q, Gao Z, et al.  . G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradio [J]. Journal of steroid biochemistry and molecular biology. 2019 Mar;187:58-67.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2