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Casein Kinase 1 Epsilon Polyclonal antibody, PBS Only

Casein Kinase 1 Epsilon Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11230-1-PBS

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Synonyms

验证数据展示

  • WB analysis of A431 using 11230-1-AP (same clone as 11230-1-PBS)

    WB analysis of A431 using 11230-1-AP (same clone as 11230-1-PBS)

    A431 cells were subjected to SDS PAGE followed by western blot with 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

    IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CSNK1E antibody included
  • IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

    IHC staining of human breast cancer using 11230-1-AP (same clone as 11230-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11230-1-AP (Casein Kinase 1 epsilon antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11230-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CSNK1E antibody included
Planning an IHC experiment? We recommend our IHCeasy CSNK1E Ready-To-Use IHC Kit. CSNK1E primary antibody included.

产品信息

11230-1-PBS targets Casein Kinase 1 Epsilon in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Casein Kinase 1 Epsilon fusion protein Ag1742 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name casein kinase 1, epsilon
Synonyms
Calculated Molecular Weight 47 kDa
Observed Molecular Weight 46-52 kDa
GenBank Accession NumberBC006490
Gene Symbol CK1 epsilon
Gene ID (NCBI) 1454
RRIDAB_2084501
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP49674
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CSNK1E(Casein kinase I isoform epsilon) is also named as CKIe, CKI-epsilon and belongs to the casein kinase I subfamily. It plays a significant role in delaying the negative feedback signal within the transcription-translation-based autoregulatory loop that composes the core of the circadian mechanism and makes an ideal target for pharmaceutical compounds influencing circadian rhythms, sleep, and jet lag, as well as other physiologic and metabolic processes under circadian regulation(PMID:10775102). It can be autophosphorylated(PMID:19690332).