验证数据展示
产品信息
67398-1-PBS targets Caspase 4 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Caspase 4 fusion protein Ag29488 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | caspase 4, apoptosis-related cysteine peptidase |
别名 | CASP4, Caspase4, Caspase 4/p20/p10, CASP-4, CASP 4 |
计算分子量 | 377 aa, 43 kDa |
观测分子量 | 43-48 kDa |
GenBank蛋白编号 | BC017839 |
基因名称 | Caspase 4 |
Gene ID (NCBI) | 837 |
RRID | AB_2882641 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P49662 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Caspase 4 (CASP4), is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspase 4 is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. Overexpression of caspase 4 will induce cell apoptosis.