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Chrysoeriol

Chrysoeriol 是一种天然黄酮，可从热带植物Coronopus didymus 中提取获得，具有强大的抗氧化功能，能够抑制脂质的过氧化。

CAS号

491-71-4

分子式

C16H12O6

主要靶点

Akt|p38 MAPK|ERK

仅限科研使用

Cat No : CM11632

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Synonyms

验证数据展示

  • CAS No.: 491-71-4

    Chrysoeriol
    CAS#: 491-71-4

产品信息

Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect.

CAS号 491-71-4
分子式 C16H12O6
主要靶点 Akt|p38 MAPK|ERK
主要通路 细胞骨架|PI3K/Akt/mTOR信号通路|MAPK信号通路
分子量 300.3
纯度 98.16%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

体外活性

Chrysoeriol significantly inhibited PDGF (20 ng/mL)-induced migration and [(3)H]-thymidine incorporation into DNA at concentrations of 5 and 10 microM without any cytotoxicity. Chrysoeriol also blocked PDGF-stimulated dissociation of actin filament and inhibited PDGF beta-receptor (Rbeta) phosphorylation in a concentration-dependent manner. As a result, the downstream signal transduction pathways of PDGF-Rbeta, including ERK1/2, p38, and Akt phosphorylation, were also inhibited by Chrysoeriol in the same pattern[1]

溶解度

DMSO:50 mg/mL (166.52 mM)

参考文献

1.An inhibitory effect of chrysoeriol on platelet-derived growth factor (PDGF)-induced proliferation and PDGF receptor signaling in human aortic smooth muscle cells.J Pharmacol Sci. 2009 May;110(1):105-10.

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The dilution calculator equation

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