Collagen Type XI Polyclonal antibody
Collagen Type XI Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IHC, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive IHC detected in | human placenta tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Planning an IHC experiment? We recommend our IHCeasy COL11A1 Ready-To-Use IHC Kit. COL11A1 primary antibody included.
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IHC | See 4 publications below |
| IF | See 3 publications below |
产品信息
21841-1-AP targets Collagen Type XI in IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | IHC, ELISA Application Description |
| Cited Applications | IF, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | Collagen Type XI fusion protein Ag16509 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | collagen, type XI, alpha 1 |
| Synonyms | CO11A1, COL11A1, COLL6, Collagen alpha 1(XI) chain, Collagen Type XI, collagen, type XI, alpha 1, STL2 |
| Calculated Molecular Weight | 1818 aa, 182 kDa |
| GenBank Accession Number | BC117697 |
| Gene Symbol | COL11A1 |
| Gene ID (NCBI) | 1301 |
| RRID | AB_2918074 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P12107 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
COL11A1 is an important component of collagen XI and is considered to play an important role in a variety of connective tissue diseases. Type XI collagen is widely distributed in tissues including cartilage, bone, and muscle, and its hereditary absence in Marshall's syndrome, Stickler's syndrome, fibrochondrogenesis, and nonsyndromic hearing loss deafness, autosomal dominant 37 leads to facial and eye abnormalities, hearing loss, and joint problems. The COL11A1 expression was significantly correlated with the degree of immune infiltration and the expression of a variety of immune cell markers in tumor tissue. (PMID: 36160004 33610546)
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for Collagen Type XI antibody 21841-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Transl Oncol Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer | ||
J Orthop Res Increased Wnt5a/ROR2 signaling is associated with chondrogenesis in meniscal degeneration | ||
BMC Med Genomics Analysis of cancer-associated fibroblasts related genes identifies COL11A1 associated with lung adenocarcinoma prognosis | ||
Front Immunol COL11A1 as an novel biomarker for breast cancer with machine learning and immunohistochemistry validation | ||