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Compstatin

Compstatin 是一种环状十三肽，是补体系统 C3的特异性抑制剂。它只抑制灵长类补体系统的激活，可结合到狒狒的 C3，并对狒狒血液中的蛋白水解裂解具有抗性。它对补体经典途径和旁路途径的 IC50值分别为 63 和 12 μM。

CAS号

206645-99-0

分子式

C66H99N23O17S2

主要靶点

Complement System

仅限科研使用

Cat No : CM04747

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Synonyms

坎普他汀

验证数据展示

  • CAS No.: 206645-99-0

    Compstatin
    CAS#: 206645-99-0

产品信息

Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.

CAS号 206645-99-0
分子式 C66H99N23O17S2
主要靶点 Complement System
主要通路 免疫与炎症
分子量 1550.77
纯度 100.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 坎普他汀

溶解度

DMSO:300 mg/mL (193.45 mM)

参考文献

1.Soulika AM, et al. Inhibition of heparin/protamine complex-induced complement activation by Compstatin in baboons. Clin Immunol. 2000 Sep;96(3):212-21.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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