验证数据展示
产品信息
66391-1-PBS targets Cyclin A2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Cyclin A2 fusion protein Ag12765 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | cyclin A2 |
别名 | CCN1, CCNA, CCNA2, Cyclin A, Cyclin A2, cyclinA2 |
计算分子量 | 432 aa, 49 kDa |
观测分子量 | 52 kDa |
GenBank蛋白编号 | BC104783 |
基因名称 | Cyclin A2 |
Gene ID (NCBI) | 890 |
RRID | AB_2881767 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P20248 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.