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DEPDC6 Polyclonal antibody, PBS Only

DEPDC6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 21312-1-PBS

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Synonyms

验证数据展示

  • WB analysis of HeLa using 21312-1-AP (same clone as 21312-1-PBS)

    WB analysis of HeLa using 21312-1-AP (same clone as 21312-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 21312-1-AP (DEPDC6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21312-1-PBS in a different storage buffer formulation.

  • IHC staining of human thyroid cancer using 21312-1-AP (same clone as 21312-1-PBS)

    IHC staining of human thyroid cancer using 21312-1-AP (same clone as 21312-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer slide using 21312-1-AP (DEPDC6 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 21312-1-PBS in a different storage buffer formulation.

产品信息

21312-1-PBS targets DEPDC6 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen DEPDC6 fusion protein Ag15959 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name DEP domain containing 6
Synonyms
Calculated Molecular Weight 409 aa, 46 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC024746
Gene Symbol DEPDC6
Gene ID (NCBI) 64798
RRIDAB_2878837
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TB45
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DEPTOR, also named as DEPDC6, is a negative regulator of the mTORC1 and mTORC2 signaling pathways. Through mTOR interactions, DEPTOR is implicated in pathways for cell growth and differentiation, as well as cell-cycle prolongation or termination. It inhibits the kinase activity of both complexes. The MW will migrate to 50-55 kDa with phospho- form.