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DMXL2 Monoclonal antibody, PBS Only

DMXL2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat, pig

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F9A8

Cat no : 66891-2-PBS

Print datasheet

Synonyms

Rabconnectin 3, KIAA0856, DmX-like protein 2, DmX like protein 2, Dmx like 2

验证数据展示

  • WB analysis of mouse cerebellum using 66891-2-Ig (same clone as 66891-2-PBS)

    WB analysis of mouse cerebellum using 66891-2-Ig (same clone as 66891-2-PBS)

    mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 66891-2-Ig (DMXL2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66891-2-PBS in a different storage buffer formulation.

  • IF Staining of Jurkat using 66891-2-Ig (same clone as 66891-2-PBS)

    IF Staining of Jurkat using 66891-2-Ig (same clone as 66891-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using DMXL2 antibody (66891-2-Ig, Clone: 1F9A8 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 66891-2-PBS in a different storage buffer formulation.

产品信息

66891-2-PBS targets DMXL2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen DMXL2 fusion protein Ag19861 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name Dmx-like 2
Synonyms Rabconnectin 3, KIAA0856, DmX-like protein 2, DmX like protein 2, Dmx like 2
Calculated Molecular Weight 3036 aa, 340 kDa
Observed Molecular Weight 340 kDa
GenBank Accession NumberBC140781
Gene Symbol DMXL2
Gene ID (NCBI) 23312
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8TDJ6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DMXL2, also named as rabconnectin-3, is a functional regulator of mammalian notch signaling with WD domains. Rabconnectin-3 is abundantly expressed in the brain where it is enriched in the synaptic vesicle fraction. Immunofluorescence and immunoelectron microscopy revealed that rabconnectin-3 was concentrated on synaptic vesicles at synapses. It may serve as a scaffold molecule for both Rab3 GEP and GAP on synaptic vesicles.