验证数据展示
产品信息
66891-2-PBS targets DMXL2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat, pig |
免疫原 | DMXL2 fusion protein Ag19861 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | Dmx-like 2 |
别名 | Rabconnectin 3, KIAA0856, DmX-like protein 2, DmX like protein 2, Dmx like 2 |
计算分子量 | 3036 aa, 340 kDa |
观测分子量 | 340 kDa |
GenBank蛋白编号 | BC140781 |
基因名称 | DMXL2 |
Gene ID (NCBI) | 23312 |
RRID | AB_2882221 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q8TDJ6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DMXL2, also named as rabconnectin-3, is a functional regulator of mammalian notch signaling with WD domains. Rabconnectin-3 is abundantly expressed in the brain where it is enriched in the synaptic vesicle fraction. Immunofluorescence and immunoelectron microscopy revealed that rabconnectin-3 was concentrated on synaptic vesicles at synapses. It may serve as a scaffold molecule for both Rab3 GEP and GAP on synaptic vesicles.