验证数据展示
产品信息
67296-1-PBS targets DOCK1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat |
免疫原 | DOCK1 fusion protein Ag18069 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | dedicator of cytokinesis 1 |
别名 | ced5, dedicator of cytokinesis 1, DOCK1, DOCK180 |
计算分子量 | 1865 aa, 215 kDa |
观测分子量 | 215 kDa |
GenBank蛋白编号 | BC146857 |
基因名称 | DOCK1 |
Gene ID (NCBI) | 1793 |
RRID | AB_2882560 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q14185 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1