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DOCK1 Monoclonal antibody, PBS Only

DOCK1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C3F12

Cat no : 67296-1-PBS

Print datasheet

Synonyms

ced5, dedicator of cytokinesis 1, DOCK1, DOCK180

验证数据展示

  • WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

  • WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

产品信息

67296-1-PBS targets DOCK1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat
Immunogen DOCK1 fusion protein Ag18069 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name dedicator of cytokinesis 1
Synonyms ced5, dedicator of cytokinesis 1, DOCK1, DOCK180
Calculated Molecular Weight 1865 aa, 215 kDa
Observed Molecular Weight 215 kDa
GenBank Accession NumberBC146857
Gene Symbol DOCK1
Gene ID (NCBI) 1793
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ14185
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1