DOCK180-Specific Polyclonal antibody

DOCK180-Specific Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA and More (1)

Conjugate

Unconjugated

Cat no : 20244-1-AP

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Synonyms

ced5, dedicator of cytokinesis 1, DOCK1, DOCK180



发表文章中的应用

IFSee 1 publications below

产品信息

20244-1-AP targets DOCK180-Specific in IF, ELISA applications and shows reactivity with human samples.

Tested Applications ELISA Application Description
Cited ApplicationsIF
Tested Reactivity human
Cited Reactivityhuman
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dedicator of cytokinesis 1
Synonyms ced5, dedicator of cytokinesis 1, DOCK1, DOCK180
Calculated Molecular Weight 215 kDa
GenBank Accession NumberNM_001380
Gene Symbol DOCK1
Gene ID (NCBI) 1793
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ14185
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1. The antibody is specific to DOCK1.

发表文章

SpeciesApplicationTitle
humanIF

Dev Cell

Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration.

Authors - Joseph H R Hetmanski