验证数据展示
Planning an IHC experiment? We recommend our IHCeasy DOCK1 Ready-To-Use IHC Kit. DOCK1 primary antibody included.
发表文章中的应用
| IF | See 1 publications below |
产品信息
20244-1-AP targets DOCK180-Specific in IF, ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | IF |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | dedicator of cytokinesis 1 |
| 别名 | ced5, dedicator of cytokinesis 1, DOCK1, DOCK180 |
| 计算分子量 | 215 kDa |
| GenBank蛋白编号 | NM_001380 |
| 基因名称 | DOCK1 |
| Gene ID (NCBI) | 1793 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q14185 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1. The antibody is specific to DOCK1.