DOK5 Polyclonal antibody
DOK5 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse liver tissue |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
11948-1-AP targets DOK5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | DOK5 fusion protein Ag2615 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | docking protein 5 |
Synonyms | C20orf180, docking protein 5, DOK5, IRS 6, IRS6 |
Calculated Molecular Weight | 306 aa, 35 kDa |
Observed Molecular Weight | 35 kDa |
GenBank Accession Number | BC008992 |
Gene Symbol | DOK5 |
Gene ID (NCBI) | 55816 |
RRID | AB_10665550 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9P104 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DOK5 belongs to the docking family of proteins that contain tandem pleckstrin homology-phosphotyrosine binding (PH-PTB) domains at their amino termini (PMID: 19909370). DOK proteins are also known as INS receptor substrates (IRS) and serve as substrates for INS and INS-like growth factor (PMID: 12730241 ) as well as various protein tyrosine kinases (PMID: 16647839). DOK5 functions as a specific signal transduction molecule and plays an important role in cellular differentiation. DOK5 is upregulated in systemic Sclerosis and Associated with IGFBP-5-Induced fibrosis (PMID: 24551065).
实验方案
Product Specific Protocols | |
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WB protocol for DOK5 antibody 11948-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |