DPP4/CD26 Monoclonal antibody
DPP4/CD26 Monoclonal Antibody for WB, IF/ICC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, pig, rabbit
Applications
WB, IF/ICC, ELISA and More (1)
Conjugate
Unconjugated
CloneNo.
2G6D11
验证数据展示
经过测试的应用
| Positive WB detected in | human placenta tissue, HuH-7 cells, pig kidney tissue, rabbit kidney tissue |
| Positive IF/ICC detected in | HuH-7 cells |
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| IF | See 1 publications below |
产品信息
68383-1-Ig targets DPP4/CD26 in WB, IF/ICC, ELISA applications and shows reactivity with human, pig, rabbit samples.
| Tested Applications | WB, IF/ICC, ELISA Application Description |
| Cited Applications | IF |
| Tested Reactivity | human, pig, rabbit |
| Cited Reactivity | human |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | dipeptidyl-peptidase 4 |
| Synonyms | CD26, ADCP-2, ADCP2, ADCP 2, ADABP |
| Calculated Molecular Weight | 88 kDa |
| Observed Molecular Weight | 110 kDa |
| GenBank Accession Number | BC013329 |
| Gene Symbol | DPP4 |
| Gene ID (NCBI) | 1803 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P27487 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CD26, also known as DPP4 (dipeptidyl peptidase-4), is a 110 kDa type II cell-surface glycoprotein widely expressed on T cells, activated B cells, activated NK cells and myeloid cells as well as on epithelial cells, fibroblasts, mesothelium, and endothelial cells of a variety of tissues (PMID:33777580; 26919392). It has ecto-enzyme activity in its extracellular domain and cleaves amino-terminal dipeptides with either L-proline or L-alanine at the penultimate position (PMID: 9553764). CD26 plays roles in diverse biological processes such as immunoregulation, glucose homeostasis, and tumorigenesis (PMID: 33777580).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for DPP4/CD26 antibody 68383-1-Ig | Download protocol |
| IF protocol for DPP4/CD26 antibody 68383-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Stem Cell Res Ther Single-cell sequencing of facial adipose tissue unveils FKBP5 as a therapeutic target for facial infiltrating lipomatosis |
