验证数据展示
产品信息
28094-1-PBS targets DRD4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, pig |
免疫原 | DRD4 fusion protein Ag26930 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | dopamine receptor D4 |
别名 | |
计算分子量 | 44 kDa |
观测分子量 | 40-44 kDa |
GenBank蛋白编号 | NM_000797 |
基因名称 | DRD4 |
Gene ID (NCBI) | 1815 |
RRID | AB_2881058 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P21917 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The family of dopamine receptors (DRs) includes five G protein-coupled receptors (GPCRs)-DRD1, DRD2, DRD3, DRD4 and DRD5-with different anatomical distribution, expression levels, dopamine affinity, signal transduction, and effector targets (PMID:36523297). DRD4 (dopamine receptor D4) influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders (PMID:21873960). Moreover, DRD4 modulate glucose metabolism, and protect neurocytes from anoxia/reoxygenation (A/R) injury. Thus, DRD4 might regulate myocardial I/R injury in association with GLUT4-mediated glucose metabolism (PMID:33584304).