验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Desmocollin 2 Ready-To-Use IHC Kit. Desmocollin 2 primary antibody included.
产品信息
84985-1-PBS targets DSC2 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | DSC2 fusion protein Ag4956 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | desmocollin 2 |
| 别名 | Desmocollin 2, Desmocollin 3, CDHF2, Cadherin family member 2, ARVD11 |
| 计算分子量 | 100 kDa |
| GenBank蛋白编号 | BC063291 |
| 基因名称 | Desmocollin 2 |
| Gene ID (NCBI) | 1824 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q02487 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelial and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in the DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.