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DSC2 Recombinant antibody, PBS Only

DSC2 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241084G9

Cat no : 84985-1-PBS

Print datasheet

Synonyms

Desmocollin 2, Desmocollin 3, CDHF2, Cadherin family member 2, ARVD11

验证数据展示

  • IF Staining of Caco-2 using 84985-1-RR (same clone as 84985-1-PBS)

    IF Staining of Caco-2 using 84985-1-RR (same clone as 84985-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Caco-2 cells using DSC2 antibody (84985-1-RR, Clone: 241084G9 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84985-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy Desmocollin 2 Ready-To-Use IHC Kit. Desmocollin 2 primary antibody included.

产品信息

84985-1-PBS targets DSC2 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen DSC2 fusion protein Ag4956 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name desmocollin 2
Synonyms Desmocollin 2, Desmocollin 3, CDHF2, Cadherin family member 2, ARVD11
Calculated Molecular Weight 100 kDa
GenBank Accession NumberBC063291
Gene Symbol Desmocollin 2
Gene ID (NCBI) 1824
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ02487
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelial and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in the DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.