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DSE Polyclonal antibody

DSE Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA and More (1)

Conjugate

Unconjugated

Cat no : 10452-1-AP

Print datasheet

Synonyms

dermatan sulfate epimerase, DS epimerase, DSE, DSEPI, SART 2, SART2

验证数据展示

  • IHC staining of human ovary tumor using 10452-1-AP

    IHC staining of human ovary tumor using 10452-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 10452-1-AP (DSE antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with DSE antibody included

经过测试的应用

Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy DSE Ready-To-Use IHC Kit. DSE primary antibody included.

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10452-1-AP targets DSE in IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Cited ApplicationsIF, IHC
Tested Reactivity human
Cited Reactivityhuman
Immunogen DSE fusion protein Ag0695 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dermatan sulfate epimerase
Synonyms dermatan sulfate epimerase, DS epimerase, DSE, DSEPI, SART 2, SART2
Calculated Molecular Weight 958 aa, 110 kDa
GenBank Accession NumberBC039245
Gene Symbol DSE
Gene ID (NCBI) 29940
RRIDAB_2093288
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UL01
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DSE, also named as SART2 and DSEPI, is an enzyme that converts D-glucuronic acid to L-iduronic acid residues in dermatan sulphate biosynthesis. It is also identified to be a tumour-associated antigen. DSE is recognized by cytotoxic T cells (CTLs) and its enhanced expression in many cancers has been reported. DSE is a potential candidate for a tumour antigen with immunogenicity.

实验方案

Product Specific Protocols
IHC protocol for DSE antibody 10452-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC, IF

Liver Int

Expression of chondroitin-glucuronate C5-epimerase and cellular immune responses in patients with hepatocellular carcinoma.

Authors - Mizukoshi Eishiro E
View Article