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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of human testis using 67226-1-Ig (same clone as 67226-1-PBS)

    WB analysis of human testis using 67226-1-Ig (same clone as 67226-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 67226-1-Ig (DUOX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

  • WB analysis of human placenta using 67226-1-Ig (same clone as 67226-1-PBS)

    WB analysis of human placenta using 67226-1-Ig (same clone as 67226-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 67226-1-Ig (DUOX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse stomach using 67226-1-Ig (same clone as 67226-1-PBS)

    IF Staining of mouse stomach using 67226-1-Ig (same clone as 67226-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse stomach tissue using DUOX1 antibody (67226-1-Ig, Clone: 3B8D6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

DUOX1 Monoclonal antibody, PBS Only

DUOX1 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 67226-1-PBS

产品说明书

CloneNo. 3B8D6

宿主/亚型

Mouse / IgG2a

种属反应性

Human, mouse

应用

WB, IF-P, Indirect ELISA

别名

dual oxidase 1, DUOX, DUOX1, Large NOX 1, LNOX1, Long NOX 1, NADPH thyroid oxidase 1, NOXEF1, THOX1, Thyroid oxidase 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67226-1-PBS targets DUOX1 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原 DUOX1 fusion protein Ag18154 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 dual oxidase 1
别名 dual oxidase 1, DUOX, DUOX1, Large NOX 1, LNOX1, Long NOX 1, NADPH thyroid oxidase 1, NOXEF1, THOX1, Thyroid oxidase 1
计算分子量 1551 aa, 177 kDa
观测分子量 190-200 kDa, 177 kDa, 138 kDa
GenBank蛋白编号BC114938
基因名称 DUOX1
Gene ID (NCBI) 53905
RRIDAB_2882515
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9NRD9
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DUOX1 (dual oxidase 1) is a calciumactivated transmembrane protein member of the NOX family of NADPH oxidases principally located on the apical surface of airway and thyroid epithelia (PMID: 28982074, 15677770, 10806195). DUOX1 is a strong generator of hydrogen peroxide (H2O2), via intra-molecular dismutation of superoxide (PMID: 25586178). Epithelial DUOX1 appears to participate in additional host defense actions, such as mucociliary clearance, and may contribute to inflammatory responses and epithelial repair processes during exogenous stress (PMID: 19386603). DUOX1 has two isofroms with the calculated molecular mass of 177 and 138 kDa, and apparent molecular mass of 180-200 kDa due to the glycosylation (PMID: 17643428, 19144650).