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Dehydrocostus Lactone

Dehydrocostus Lactone ((-)-Dehydrocostus lactone) 是一种倍半萜内酯，从云木香中分离得到。

CAS号

477-43-0

分子式

C15H18O2

主要靶点

IκB/IKK

仅限科研使用

Cat No : CM00599

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Synonyms

Epiligulyl oxide|(-)-Dehydrocostus lactone|去氢木香内酯|去氢木香烃内酯

验证数据展示

  • CAS No.: 477-43-0

    Dehydrocostus Lactone
    CAS#: 477-43-0

产品信息

Dehydrocostus shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

CAS号 477-43-0
分子式 C15H18O2
主要靶点 IκB/IKK
主要通路 NF-κB信号通路
分子量 230.3
纯度 98.15%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Epiligulyl oxide|(-)-Dehydrocostus lactone|去氢木香内酯|去氢木香烃内酯

溶解度

DMSO:60 mg/mL (260.52 mM)

参考文献

1.Dong GZ, et al. PhytOthers Res. 2015 May;29(5):680-6.
2.Nie Y, Wang Z, Chai G, et al. Dehydrocostus Lactone Suppresses LPS-induced Acute Lung Injury and Macrophage Activation through NF-κB Signaling Pathway Mediated by p38 MAPK and Akt[J]. Molecules. 2019 Apr 17;24(8). pii: E1510.
3.Chen Y, Li R, Wang Z, et al. Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo[J]. Cellular Immunology. 2020, 349: 104046.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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=
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C1   V1   C2   V2