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Desmocollin 2 Monoclonal antibody, PBS Only

Desmocollin 2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H8G1

Cat no : 60239-1-PBS

Print datasheet

Synonyms

ARVD11, Cadherin family member 2, CDHF2, desmocoilin, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3

验证数据展示

  • WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy Desmocollin 2 Ready-To-Use IHC Kit. Desmocollin 2 primary antibody included.

产品信息

60239-1-PBS targets Desmocollin 2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen Desmocollin 2 fusion protein Ag5450 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name desmocollin 2
Synonyms ARVD11, Cadherin family member 2, CDHF2, desmocoilin, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3
Calculated Molecular Weight 100 kDa
Observed Molecular Weight 110 kDa
GenBank Accession NumberBC063291
Gene Symbol Desmocollin 2
Gene ID (NCBI) 1824
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ02487
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.