验证数据展示
产品信息
60239-1-PBS targets Desmocollin 2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | Desmocollin 2 fusion protein Ag5450 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | desmocollin 2 |
Synonyms | ARVD11, Cadherin family member 2, CDHF2, desmocoilin, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3 |
Calculated Molecular Weight | 100 kDa |
Observed Molecular Weight | 110 kDa |
GenBank Accession Number | BC063291 |
Gene Symbol | Desmocollin 2 |
Gene ID (NCBI) | 1824 |
RRID | AB_2881362 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q02487 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.