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Desoxyrhaponticin

Desoxyrhaponticin (Deoxyrhaponticin) 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂，抑制细胞内 FAS 活性，下调人乳腺癌 MCF-7细胞中 FAS 的表达。它是控制糖尿病餐后高血糖的潜在药物。

CAS号

30197-14-9

分子式

C21H24O8

主要靶点

Fatty Acid Synthase|Apoptosis

仅限科研使用

Cat No : CM18396

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Synonyms

Deoxyrhapontin|脱氧土大黄苷|去氧土大黄苷|Deoxyrhaponticin

验证数据展示

  • CAS No.: 30197-14-9

    Desoxyrhaponticin
    CAS#: 30197-14-9

产品信息

1. Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney. 2. Desoxyrhaponticin and rhaponticin could be considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.

CAS号 30197-14-9
分子式 C21H24O8
主要靶点 Fatty Acid Synthase|Apoptosis
主要通路 代谢|凋亡
分子量 404.41
纯度 99.88%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Deoxyrhapontin|脱氧土大黄苷|去氧土大黄苷|Deoxyrhaponticin

溶解度

DMSO:50 mg/mL (123.64 mM)

参考文献

1.Li P , Tian W , Wang X , et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan medicinal plant Rheum tanguticum Maxim. ex Balf, on fatty acid synthase and human breast cancer cells[J]. Food & Function, 2014, 5(2):251-256.

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