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Dirithromycin

Dirithromycin (LY237216) 是一种红霉素衍生物，是一种具有口服活性的半合成大环内酯类抗生素。它用于治疗许多不同类型的细菌感染。

CAS号

62013-04-1

分子式

C42H78N2O14

主要靶点

Antibacterial|ribosome|Antibiotic

仅限科研使用

Cat No : CM00214

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Synonyms

Dirithromycine|ASE 136|Diritromicina|LY237216|Dirithromycinum|地红霉素

验证数据展示

  • CAS No.: 62013-04-1

    Dirithromycin
    CAS#: 62013-04-1

产品信息

Dirithromycin is a macrolide glycopeptide antibiotic. It is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.

CAS号 62013-04-1
分子式 C42H78N2O14
主要靶点 Antibacterial|ribosome|Antibiotic
主要通路 微生物学
分子量 835.07
纯度 98.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Dirithromycine|ASE 136|Diritromicina|LY237216|Dirithromycinum|地红霉素

体内活性

Dirithromycin在治疗浓度下,增强脂多糖刺激细胞产生的IL1β,在1 μg/mL下分别增强+37 % 和+28%。Dirithromycin在超治疗浓度下,其通过抑制蛋白激酶C而抑制IL1β,抑制率为50%时,Dirithromycin浓度为378 mg/mL,螺旋霉素的浓度为234 mg/mL。

溶解度

H2O:<1 mg/mL,DMSO:9 mg/mL (10.8 mM),Ethanol:93 mg/mL (111.4 mM)

参考文献

1.Moutard I, et al. Therapie, 1999, 54(5), 607-612.
2.Arda B, et al. Int J Antimicrob Agents, 2004, 23(2), 204-207.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2