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Dynamitin (1-401 AA) Monoclonal antibody, PBS Only

Dynamitin (1-401 AA) Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG3

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2B9A5

Cat no : 60257-1-PBS

Print datasheet

Synonyms

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50

验证数据展示

  • WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

    WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 60257-1-Ig (Dynamitin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

产品信息

60257-1-PBS targets Dynamitin (1-401 AA) in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen Dynamitin (1-401 AA) fusion protein Ag1902 种属同源性预测
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Full Name dynactin 2 (p50)
Synonyms DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50
Calculated Molecular Weight 401 aa, 44 kDa
Observed Molecular Weight 52+150 kDa
GenBank Accession NumberBC014083
Gene Symbol Dynamitin
Gene ID (NCBI) 10540
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13561
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.