EAAT2 activator 1

EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) 是兴奋性氨基酸转运蛋白 2(EAAT2) 的有效激活剂,以剂量依赖性方式增加 EAAT2 蛋白水平。

CAS号

892415-28-0

分子式

C16H11ClFN3S

主要靶点

transporter

仅限科研使用

Cat No : CM15205

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Synonyms

3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine



产品信息

F2005-0304 is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.

CAS号 892415-28-0
分子式 C16H11ClFN3S
主要靶点 transporter
主要通路 代谢
分子量 331.8
纯度 99.63%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine

溶解度

DMSO:16.25 mg/ml (48.98 mM)

参考文献

1.Xing X, et al. Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5774-7.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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