• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

EG1

EG1 是特异性 Pax2<.b> 抑制剂，能够直接结合 Pax2 的配对结构域 (Kd:1.35-1.5 μM) ，可阻碍 Pax2-DNA 相互作用。它能够抑制胚胎肾脏发育，此过程直接依赖于 Pax2活性。

CAS号

693241-54-2

分子式

C22H18N2O5

主要靶点

Others

仅限科研使用

Cat No : CM05761

Print datasheet

Synonyms

验证数据展示

  • CAS No.: 693241-54-2

    EG1
    CAS#: 693241-54-2

产品信息

EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.

CAS号 693241-54-2
分子式 C22H18N2O5
主要靶点 Others
主要通路 其他
分子量 390.39
纯度 97.73%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

溶解度

DMSO:70mg/ml(179.31mM),Sonification is recommended.

参考文献

1.Smith CB, Phillips T, Smith TJ. Using the New ASCO Clinical Practice Guideline for Palliative Care Concurrent With Oncology Care Using the TEAM Approach. Am Soc Clin Oncol Educ Book. 2017;37:714-723. doi: 10.14694/EDBK_175474. PubMed PMID: 28561696.
2.Masuda K, Ono A, Aikata H, Kawaoka T, Nelson Hayes C, Teraoka Y, Daijo K, Nakamura-Inagaki Y, Morio K, Fujino H, Kan H, Uchida T, Masaki K, Kobayashi T, Nakahara T, Makokha GN, Zhang Y, Nagaoki Y, Miki D, Tsuge M, Hiramatsu A, Imamura M, Abe-Chayama H, Kawakami Y, Ochi H, Chayama K. Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy. J Gastroenterol. 2017 May 29. doi: 10.1007/s00535-017-1352-z. [Epub ahead of print] PubMed PMID: 28555325.
3.Germain D. Toward the identification and the targeting of key players of the mitochondrial unfolded protein response (UPR(mt)) in cancer. J Bioenerg Biomembr. 2017 May 29. doi: 10.1007/s10863-017-9716-x. [Epub ahead of print] PubMed PMID: 28555290.
4.Molotkov A, Mazot P, Brewer JR, Cinalli RM, Soriano P. Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency. Dev Cell. 2017 May 23. pii: S1534-5807(17)30386-6. doi: 10.1016/j.devcel.2017.05.004. [Epub ahead of print] PubMed PMID: 28552557.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2