验证数据展示
经过测试的应用
| Positive WB detected in | rat eye tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19291-1-AP targets EGFL7 in WB, IHC, IF, ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | EGFL7 fusion protein Ag6559 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | EGF-like-domain, multiple 7 |
| 别名 | Multiple EGF-like domains protein 7, MEGF7, Epidermal growth factor-like protein 7, EGF-like protein 7, EGF like protein 7 |
| 计算分子量 | 273 aa, 30 kDa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | BC012377 |
| 基因名称 | EGFL7 |
| Gene ID (NCBI) | 51162 |
| RRID | AB_10643993 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9UHF1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for EGFL7 antibody 19291-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Blood Adv The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.
| ||
Mol Ther Nucleic Acids Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay. | ||
Sci China Life Sci Role of EGFL7/EGFR-signaling pathway in migration and invasion of growth hormone-producing pituitary adenomas. | ||
Hum Gene Ther Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion. | ||
Tumour Biol EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway. |