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Species Reactivity
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Species Reactivity
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验证数据展示

  • WB analysis using 11440-1-AP (same clone as 11440-1-PBS)

    WB analysis using 11440-1-AP (same clone as 11440-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11440-1-AP (EHD2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse heart using 11440-1-AP (same clone as 11440-1-PBS)

    IP experiment of mouse heart using 11440-1-AP (same clone as 11440-1-PBS)

    IP result of anti-EHD2 (IP:11440-1-AP, 4ug; Detection:11440-1-AP 1:800) with mouse heart tissue lysate 4000ug. This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11440-1-AP (same clone as 11440-1-PBS)

    IHC staining of human breast cancer using 11440-1-AP (same clone as 11440-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11440-1-AP (EHD2 antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EHD2 antibody included
  • IHC staining of human breast cancer using 11440-1-AP (same clone as 11440-1-PBS)

    IHC staining of human breast cancer using 11440-1-AP (same clone as 11440-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11440-1-AP (EHD2 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EHD2 antibody included
  • IHC staining of human colon using 11440-1-AP (same clone as 11440-1-PBS)

    IHC staining of human colon using 11440-1-AP (same clone as 11440-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human normal colon slide using 11440-1-AP (EHD2 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EHD2 antibody included
  • IHC staining of human colon using 11440-1-AP (same clone as 11440-1-PBS)

    IHC staining of human colon using 11440-1-AP (same clone as 11440-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human normal colon slide using 11440-1-AP (EHD2 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11440-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EHD2 antibody included
  • Featured Product
  • KD/KO验证

EHD2 Polyclonal antibody, PBS Only

EHD2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 11440-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

PAST2, PAST homolog 2, EH domain-containing protein 2, EH domain containing protein 2, EH domain containing 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy EHD2 Ready-To-Use IHC Kit. EHD2 primary antibody included.

产品信息

11440-1-PBS targets EHD2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 EHD2 fusion protein Ag2002 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 EH-domain containing 2
别名 PAST2, PAST homolog 2, EH domain-containing protein 2, EH domain containing protein 2, EH domain containing 2
计算分子量 543 aa, 61 kDa
观测分子量 61 kDa
GenBank蛋白编号BC014445
基因名称 EHD2
Gene ID (NCBI) 30846
RRIDAB_2097325
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NZN4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EH domain-containing protein 2 (EHD2) is a member of the EHD protein family. It is primarily located in the plasma membrane but can also be found in the cytoplasm and endosomes. EHD2 is also a nuclear-cytoplasmic shuttle protein, acting as a corepressor of transcription to inhibit gene transcription when it enters the cell nucleus. EHD2 is a dynamin-related ATPase that plays a key role in regulating a series of biological processes. As a crucial regulator of endocytic transport, it is involved in the formation and maintenance of endosomal tubules and vesicles, which are vital for intracellular transport of proteins and other substances. EHD2 has been implicated in several human cancers and has potential as a predictive biomarker of chemotherapy efficacy.