ELA2 Polyclonal antibody
ELA2 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat and More (1)
Applications
ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy ELANE/ELA2 Ready-To-Use IHC Kit. ELANE/ELA2 primary antibody included.
发表文章中的应用
| IF | See 1 publications below |
产品信息
The immunogen of 17943-1-AP is ELA2 Fusion Protein expressed in E. coli.
| Tested Applications | ELISA Application Description |
| Cited Applications | IF |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | bovine |
| Immunogen | ELA2 fusion protein Ag12372 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | elastase 2, neutrophil |
| Synonyms | Bone marrow serine protease, ELA2, ELANE, Elastase 2, elastase 2, neutrophil, GE, HLE, HNE, Human leukocyte elastase, Medullasin, NE, Neutrophil elastase, PMN E, PMN elastase |
| Calculated Molecular Weight | 267 aa, 29 kDa |
| GenBank Accession Number | BC074816 |
| Gene Symbol | ELA2 |
| Gene ID (NCBI) | 1991 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P08246 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ELA2(Neutrophil elastase) is also named as ELAL, NE, HLE, HNE, PMN-E, SERP1, GE, ELANE and belongs to the peptidase S1 family. It is a 33-kDa enzyme with several isoforms that differ in their extent of glycosylation(PMID:12223222). Human neutrophil elastase (HNE) is a serine protease with potent proteolytic activity (3), which is reported to cause mucin secretion (degranulation)(PMID:12169572). It may contribute to the directed migration of leukocytes into flamed postcapillary venules in addition to contributing to the process of tissue emigration(PMID:9683424). The full length protein has a signal peptide,propeptide and three glycosylation sites.
发表文章
| Species | Application | Title |
|---|---|---|
Biol Trace Elem Res Effect of Copper, Zinc, and Selenium on the Formation of Bovine Neutrophil Extracellular Traps. | ||
Cell Death Discov Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection. |