验证数据展示
产品信息
84235-4-PBS targets ENTPD1 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Recombinant Protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | ectonucleoside triphosphate diphosphohydrolase 1 |
别名 | CD39/ENTPD1, CD39, ATP-DPH, ATPDase, ATP diphosphohydrolase |
计算分子量 | 58 kDa |
观测分子量 | 75 kDa |
GenBank蛋白编号 | BC047664 |
基因名称 | CD39 |
Gene ID (NCBI) | 953 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | P49961 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named CD39, NTPDase 1, and Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system, it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. It is a noncovalent tetrameric protein and detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers(PMID: 9733785 ). And it is a 70- to 100-kDa protein that is heavily N-glycosylated(PMID:7930580). This protein has 6 glycosylation sites and 3 isoforms(58 kDa, 59 kDa, and 34 kDa) produced by alternative splicing.