验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 66667-1-Ig
产品信息
CL488-66667 targets EPHA7 in applications and shows reactivity with Human, Mouse, Rat, Pig samples.
| 经测试应用 | Application Description |
| 经测试反应性 | Human, Mouse, Rat, Pig |
| 免疫原 | EPHA7 fusion protein Ag3813 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | EPH receptor A7 |
| 别名 | EPH homology kinase 3, EK11, EHK-3, EHK3, EHK 3 |
| 计算分子量 | 998 aa, 112 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | BC027940 |
| 基因名称 | EPHA7 |
| Gene ID (NCBI) | 2045 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q15375 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Ephrin receptor A7 (EphA7) is a member of the Eph receptor family. EPHA7 plays a role in corticogenesis processes, determines brain size and shape, and is involved in development of the central nervous system (PMID:34176129). In addition, EphA7 also has a dual role of tumor promoter and tumor suppressor. It can participate in cell proliferation, migration and apoptosis through various mechanisms, and afect tumor diferentiation, staging and prognosis. EphA7 may be a potential diagnostic marker and tumor treatment target (PMID:35112312).